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Symbol
Name
ID
Trim8
tripartite motif-containing 8
MGI:1933302
Phenotype annotations related to immune system
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations

Mouse Phenotypes
immune system phenotype
increased macrophage cytokine production
abnormal circulating chemokine level
increased circulating interleukin-6 level
increased circulating tumor necrosis factor level
abnormal chemokine secretion
increased interferon-beta secretion
decreased interleukin-6 secretion
increased interleukin-6 secretion
decreased tumor necrosis factor secretion
increased tumor necrosis factor secretion
increased susceptibility to endotoxin shock
increased susceptibility to bacterial infection
increased susceptibility to bacterial infection induced morbidity/mortality
Availability Mouse Genotype
Trim8tm1Hbsh/Trim8tm1Hbsh *

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory