Symbol Name ID |
Trim8
tripartite motif-containing 8 MGI:1933302 |
* | Aspects of the system are reported to show a normal phenotype. |
Darker colors indicate more annotations |
Mouse Phenotypes | immune system phenotype |
increased macrophage cytokine production |
abnormal circulating chemokine level |
increased circulating interleukin-6 level |
increased circulating tumor necrosis factor level |
abnormal chemokine secretion |
increased interferon-beta secretion |
decreased interleukin-6 secretion |
increased interleukin-6 secretion |
decreased tumor necrosis factor secretion |
increased tumor necrosis factor secretion |
increased susceptibility to endotoxin shock |
increased susceptibility to bacterial infection |
increased susceptibility to bacterial infection induced morbidity/mortality |
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Availability | Mouse Genotype | ||||||||||||||
Trim8tm1Hbsh/Trim8tm1Hbsh | * |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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